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Prof. Dr. Mushtaq Hussain

Prof. Dr. Mushtaq Hussain

Name

Prof. Dr. Mushtaq Hussain

Designation

Professor and Principal

Email

mushtaq.hussain@duhs.edu.pk

Office

Dow College of Biotechnology, Serobiology Building, 3rd Floor, DUHS, Ojha Campus

Qualifications

PhD in Genetics, Genomics and Systems Medicine, University of Glasgow

 https://orcid.org/0000-0001-8862-179X

Research

  • •    Israr F, ul Hasan SM, Hussain M*, Qazi, FR, Hasan A. 2023. Investigating In situ Expression of Neurotrophic Factors and Partner Proteins in Irreversible Pulpitis. J. Endodont.
     
  • •    Khan N, Perveen K, Hussain M*, Malik RQ, Sharafat S. 2023. Anatomical transition of trilaminar cerebellar cortex between reptiles and Aves. Adv. Life Sci. 10: 259-64.
     
  • •    Amanullah A, Arzoo S, Aslam A, Qureshi IW, Hussain M*. 2023. Inbreeding Driven Changes in the Innate Behavior of Drosophila melanogaster. Biology. 12: 926.
     
  • • Mustansar T, Mirza T, Hussain M*. 2023. RAS gene mutations and histomorphometric measurements in Oral Squamous Cell Carcinoma. Biotechnic Histochem. 1-9.
     
  • • Khan N, Perveen K, Hussain M*, Malik RQ, Sharafat S. 2023. Comparative Histological Analysis of Cerebellum of Representative Species of Elasmobranchii. Int. J. Morphol. 41(2):383-388.
     
  • • Kamran DS, Hussain M*, Mirza T. 2023. Investigating In Situ Expression of c-MYC and Candidate Ubiquitin-Specific Proteases in DLBCL and Assessment for Peptidyl Disruptor Molecule against c-MYC-USP37 Complex. Molecules. 28:2441.
     
  • • Hussain M, Siddiqui F, Omer SM, Amanullah A, Jabeen N, Kantarcioglu B, Fareed J. 2022. Molecular Systems Network Predicts Sars-Cov-2 NSP3 and Orf6 Role in COVID-19 Related Thrombotic Events. Blood. 140:11216-7.
     
  • • Hussain M*, Amanullah A, Aslam A, Raza F, Arzoo S, Qureshi IW, Waheed H, Jabeen N, Shabbir S, Sayeed MA, Quraishy S. 2022. Design and immunoinformatic assessment of candidate multivariant mRNA vaccine construct against immune escape variants of SARS-CoV-2. Polymers. 14(16):3263.
     
  • •Zainulabid UA, Mat Yassim AS, Hussain M*, Aslam A, Soffian SN, Mohd Ibrahim MS, Kamarudin N, Kamarulzaman MN, Hin HS and Ahmad HF. 2022. Whole genome sequence analysis showing unique SARS-CoV-2 lineages of B. 1.524 and AU. 2 in Malaysia. PloS one. 17(2):e0263678.
     
  • • Batool TS, Hussain M, Masnoon J, Abdullah A, Ali S, Shahzad S and Raza S. 2021. Investigating sequence variation in PNPi protein gene of Puccinia Striiformis f.sp tritici and its interaction with wheat NPR1 protein. J. Plant Pathol.
     
  • • Raza F and Hussain M*. 2021. Birth and Death of CYLD Paralogues in Vertebrates. Gene Reports. 24: 101190
     
  • • Hussain M*, Shabbir S, Amnaullah A, Raza F, Imdad MJ and Zahid S. 2021. Immunoinformtic Analysis of Structural and Epitope Variations in Spike and Orf8 Proteins of SARS-CoV-2/B.1.1.7. J. Med. Virol. 93:4461-4468.
     
  • • Arzoo S, Naqvi Z, Hussain M*, Shamim S, Zeb TM, Ali S. 2020. Production and Antimicrobial Activity of Silver Nanoparticles Synthesized from Indigenously Isolated Pseudomonas aeruginosa from Rhizosphere. Pak. J. Pharm. Sci. 33:6: Suppl.
     
  • • Mughal M, Hussain M*, Amjad Z, Perveen K, Mustansar T. 2020. Expression of Tp53 and USP7 during development of lungs in mouse model. Int. J. Endorsing Health Sci. Research. 8: 173-179.
     
  • • Hussain M*, Jabeen N, Amanullah A, Baig AA, Aziz B, Shabbir S, Raza F, Uddin N. 2020. Molecular docking between human TMPRSS2 and SARS-CoV-2 spike protein: conformation and intermolecular interactions. AIMS Microbiol. 6: 350-360.
     
  • • Khan MA, Ali S, Shamim S, Ahmed N, Hussain M, Farooq S, Khan S. 2020. Antimicrobial and synergistic activity of thiazoline derivatives in combination with conventional antibiotics against multidrug resistant Staphylococcus aureus isolated from abscess drainage samples. Pak. J. Pharm. Sci. 33:5: Suppl. 2331-2339.
     
  • • Nasiruddin, Hussain M*, Rauf I and Zaidi SF. 2020. Identification of Key Pathways and Genes Responsible for Aggressive Behavior. J. Comp. Biol. Chem. 88: 107349.
     
  • • Hussain M*, Jabeen N, Shabbir S, Nasiruddin, Aziz B, Amanullah A, Raza F and Baig AA. 2020. Dataset for Homologous Proteins in Drosophila melanogaster for SARS-CoV-2/Human Interactome. Data Brief. 32: 106082.
     
  • • Hussain M*, Jabeen N, Raza F, Shabbir S, Baig AA, Amanullah A and Aziz B. 2020. Structural Variations in Human ACE2 may Influence its Binding with SARS‐CoV‐2 Spike Protein. J. Med. Virol. 92: 1580-1586.
     
  • • Muhammad SD, Khan H, Hussain M*, Zeb TM, Kumar D, Rahi R, Asif M and Baloch AA. 2020. Pharmacogenetics of sulfonylurea: Presence of CYP2C9*2, CYP2C9*3 and a novel allele, CYP2C9*61, in Type 2 diabetes patients under sulfonylurea therapy. Pak. J. Pharm. Sci. 33:4: Suppl. 1771-1777.
     
  • • Shakir S and Hussain M*. 2017. Cancer Molecular Medicine: Targeting C-Myc and USP37 Interactions. Biomed Research Therapy. 4:S56.
     
  • • Mustansar T, Mirza T. and Hussain M*. 2016. Molecular oncology: Structural and functional impact of mutations in RAS gene family. Eur. J. Pathol. 469: S40.
     
  • • Shahab N, Perveen K. and Hussain M*. 2016. Sticking to traditions: Anatomy education and research in Pakistan. Anat. Sci. Educ. 9: 101-102.
     
  • • Khalique A, Shakir S, Qureshi MA. And Hussain M.* 2015. Evolution and clinical science: Still a long bridge to build. J. Evo. Med. 3: 35.
     
  • • Hussain M, Gatherer D. and Wilson JB. 2014. Modelling the structure of full-length Epstein- Barr virus nuclear antigen 1. Virus Genes. 49:358-72.
     
  • • Jabeen N, Hussain M, Khan JA, Naz SA. and Rasool SA. 2014. Biophysicochemical characterization and applied Cartovoricin NA5 (CrNA5) from Erwinia carotovra NA5. Pak. J. Bot. 46: 2249-2256.
     
  • • Hussain M*and Mushtaq A. 2013. Backing up the forensic DNA evidence. Nature. 503: 342.
     
  • • Hussain M and Wilson JB. 2013. New paralogues and revised time line in the expansion of the vertebrate GH18 family. J. Mol. Evo.76:240-260.
     
  • • Raza S, Qamurnnisa S, Hussain M, Jamil I, Anjum S, Azhar A. and Qureshi JA. 2012. Regeneration of sugarcane via somatic embryogenesis and genomic instability in the regenerated plants. J. Crop. Sci. Biotech. 15: 131-136.
     
  • • Qamurnnisa S, Hussain M, Jabeen N, Raza S, Khanani MR, Azhar A, Qureshi JA. and Naqvi SHM. 2012. In silico studies on structure-function of DNA GCC box binding domain of B. napus DREB1 protein. Pak. J. Bot. 44: 493-500.
     
  • • Hussain M, Jabeen N, Wajid A, Khanani MR, Hasan SK. and Rasool SA. 2012. Evolutionary root defines the structural basis of high and low level vancomycin resistance in enterococci. Pak. J. Pharm. Sci. 25: 43-50.
     
  • • Shakir S, Waseem WA, Hasan SK, Munir M, Khanani MR. and Hussain M*. 2011. Structural Phylogenomics: Selection pressure suggest the functionally important residues encoded by cisplatin resistance related 9 gene. JDUHS. 5: 111-117.
     
  • • Hussain M, Khanani MR, Jabeen N, Sharafat SS. and Mirza T. 2010. Protein homology modelling and structure function relationship of 2009 swine flu influenza virus heamglutinin (HA1): more human than swine. Biologia (Cell and Molecular Biology). 65: 183-190.
     
  • • Hussain M, Qureshi MA, Khanani MR, Wajid A, Sharafat SS. and Mirza T. 2010. Microcephaly: Tracing the evolutionary lineage of ASPM gene. JDUHS. 4: 73-77.
     
  • • Jabeen N, Gul H, Subhan SA, Hussain M, Ajaz M. and Rasool SA. 2009. Biophysicochemical characterization of bacteriocins from indigenously isolated Aarobacterium radiobacter NA6. Pak. J. Bot. 41: 3227-3237.
     
  • • Hussain M, Qamarunnisa S, Raza S, Qureshi J, Wajid A. and Rasool SA. 2009. DNA photolyase -of enterococci: possible explanation of its low sunlight inactivation rate. Biologia (Cell and Molecular Biology). 64: 852-858.
     
  • • Hussain M, Qureshi, JA, Shaikh SA. and Sultana L. 2008. Phylogenetic and Computational Structure-Function Studies of α1-4 glucosidase from Baker’s yeast. Pak. J. Sci. Ind. Res. 51: 185-190.
     
  • • Khan M., Hussain M, Wajid A. and Rasool SA. 2008. Microbial population load and enzyme production of indigenously isolated yeast. Pak. J. Bot. 40: 2225-2230.
     
  • • Hussain M, Khan MT, Wajid A. and Rasool SA. 2008. Technological characterization of indigenous enterococcal population for probiotic potential. Pak. J. Bot. 40: 867-875.
     
  • • Hussain M, Khan MT. and Wajid A. 2007. Exploring vertical and horizontal gene transfer and P.multocida PM70 by comparative genomic studies. Int. J. Biol. Biotech. 4: 15-18.
     
  • • Hussain M, Rasool SA, Khan MT. and Wajid A. 2007. Enterococci vs coliform as a possible faecal contamination indicator: Baseline data for Karachi. Pak. J. Pharm. Sci. 20: 107-111