Name
Dr. Saima Mahmood Malhi
Designation
Associate Professor
saima.mahmood@duhs.edu.pk
Office
Building A, Dow College of Pharmacy, Faculty of Pharmaceutical Sciences, Ojha Campus, Karachi
Qualifications
B Pharmacy, Baqai Medical University
MPhil (Pharmacology), Faculty of Pharmacy, University of Karachi
PhD (Pharmacology), ICCBS, University of Karachi
Research
1. Malhi, S.M., Raza, M., Ahmed, S.P. Investigation of anti-Parkinson activities in Withania somnifera, Acorus calamus and related medicinal plants of Pakistan. Physiology and Pharmacology, Supplement 1: 42 (2006), Tehran, Iran.
2. Rehana Perveen, R., Naqvi, S.N.H., Azmi, M.A., Tariq, R.M., Ahmed and Mahmood, S. “Determination of mammalian toxicity of Cedarus deodara root oil, against albino rats (Wistar strain)”. Pakistan Journal of Entomology, Karachi 23(1&2): 1-4(2008).
3.Saima Mahmood Malhi1,3, Farina Hanif2, Huma Jawed1, Nadeem Ashraf1, Farhat1, Bina S. Siddiqui1, Sabira Begum1, Shabana Usman Simjee1,2 . Modulation of behavioral and molecular markers in PTZ-kindled mice following the treatment with novel anti-epileptic compound. FENS-IBRO workshop on “Drugs and Brain”, 15th-20 th April, (2012), University of Minho, Braga, Portugal.
4. Farina Hanif; Saima Mehmood Malhi; Huma Javed; Nadeem Ashraf; Farhat; Bina Siddiqui; Sabira Begum and Shabana Usman Simjee. HHL-6 downregulates BDNF expression in PTZ-induced kindling model of epilepsy in mice. APRC: 2nd Tehran IBRO School of Neuroscience: Molecular, Electrophysiological and Behavioral Approaches. May 12-23, (2012), Tehran Iran (2nd Prize).
5. Saima Mahmood Malhi1, 3, Huma Jawed1, Farina Hanif2,, Nadeem Ashraf1, Farhat1, Bina Siddiqui1, Sabira Begum1, Shabana Usman Simjee1,2 . Modulation of c-Fos and BDNF proteins expression in PTZ-kindled mice following the treatment with novel anti-epileptic compound 2-Acetyl-3-(2-Hexanoylamidoethyl)-7-methoxyindole: An Immunohistochemical analysis. 10th ILAE European Congress on Epileptology (ECE), Sep 30th- Oct 4th (2012), London.
6. Sumbul Shamim1*, Saima Mahmood Malhi1, Muhammad Riaz Bhatti2, Beena Khan3and Tahir Yousuf3. Frequency of lower respiratory tract infections in Karachi and comparison of different antibiotic agents used for the treatment. Scientific Research and Essays Vol. 7(30), pp. 2691-2698, 2 August, 2012.
7. Saima Mahmood Malhi1,3, Huma Jawed1, Farina Hanif2, Nadeem Ashraf1, Farhat1, Bina S. Siddiqui1, Sabira Begum1, Nurul Kabir, Shabana Usman Simjee1,2 . Modulation of c-Fos and BDNF protein expression in PTZ-kindled mice following the treatment with novel anti-epileptic compound HHL-6. (BioMed Research International; 2014) [Article ID 876712, 9 pages; http://dx.doi.org/10.1155/2014/876712].
8. Faizan Mazhar, Sumbul Shamim, *Saima Mahmood Malhi. Drug Utilization Evaluation Of Antiepileptics In Three Selected Multidisciplinary Teaching Hospitals Of Pakistan. (International Journal of Pharmacy and Pharmaceutical Sciences, 6(5): 59-66, 2014).
9. Farina Hanif, Kahkashan Perveen, Huma Jawed, Aqeel Ahmed, Saima M Malhi, Siddiqua Jamall, Shabana U Simjee. N-(2-hydroxyphenyl) acetamide (NA-2) and Temozolomide synergistically induce apoptosis in human glioblastoma cell line U87. (Cancer Cell International, 14:133, November, 2014).[ doi:10.1186/s12935-014-01335]
10. Malhi S., Mazhar F., Chaudhary M., Shaheen F., Simjee S. Essential oil from Aconitum cochleare modulates the gene expression of BDNF, TrkB and oxidative stress parameters in a mouse model of epileptogenesis with safe toxicity profile". 10th Asian & Oceanian Epilepsy Congress (AOEC), August, 2014, Singapore.
11. *Saima Mahmood Malhi, *Hassan Raza, Kiran, Ajmal, Sumbul Shamim, Saniya Atta, Salman Farooq, Syed Sharib, Sidrat-ul-Muntaha. Current status and development of pharmacy curriculum towards pharmacy practice in Pakistan. (2017, Journal of ‘Pharmacy” in the section of Pharmacy education and students and professionals training.)
12. *Sumbul Shamim, Syed Muhammad Sharib, *Saima Mahmood Malhi, Sidrat-ul Muntaha, Hassan Raza, Saniya Ata, Ali Salman Farooq, Mehwish Hussain. Adverse drug reactions (ADRS) reporting: awareness and reasons of under-reporting among health care professionals, a challenge for pharmacists. Springer Plus, 2016; 5:1778. (DOI: 10.1186/s40064-016-3337-4).
13. Faizan Mazhar, Saima Mahmood Malhi, Shabana Usman Simjee. Comparative studies on effects of clinically used anticonvulsants on the oxidative stress biomarkers in PTZ-induced Kindling Model of Epileptogenesis in mice. Journal of Pharmacological and Toxicological Methods, 70(3):313, November-December, 2014.
14. Saima Mahmood Malhi, Faizan Mazhar, Farzana Shaheen, M. Iqbal Chaudhary, Shabana Usman Simjee. Aconitum cochleare Woroschin-oil attenuates the molecular markers of epileptogenesis in kindled mice with safe toxicity profile. (Manuscript in process).
15. Faizan Mazhar, Saima Mahmood Malhi, Shabana Usman Simjee. Anticonvulsant and anti-oxidative stress properties of ACR-oil. Journal of Pharmacological and Toxicological Methods, Volume 70, Issue 3, Page 313, November-Decembeer, 2014.
16. Faizan Mazhar*, Saima M. Malhi and Shabana U. Simjee. Comparative studies on the effects of clinically used anticonvulsants on the oxidative stress biomarkers in pentylenetetrazole-induced kindling model of epileptogenesis in mice. J Basic Clin Physiol Pharmacol 2016; aop. (DOI 10.1515/jbcpp-2016-0034).
17. Incorporating a clinical oncology pharmacist into an ambulatory care pharmacy in pediatric hematology–oncology and transplant clinic: Assessment and significance, Journal of Oncology Pharmacy Practice, July, 2020. Kashif Ali , Osama Al-Quteimat, Rida Naseem, Saima Mahmood Malhi, Mehwish wajdi, Noor Jahan, Saqib Hussain Ansari, . Tahir Sultan Shamsi. https://doi.org/10.1177/1078155220934167
18. Diclofenac sodium enhances the antiepileptic effect of levetiracetam in pilocarpine induced epileptic mice model. Lalarukh Javed, Farina Hanif, Saima Mahmood Malhi, Uzma Zaman, Noor Jahan, Quratulain Amir, Ariba Javed, Ayesha Batool Malik and Hina Abrar). (Accepted in Pakistan Journal of Pharmaceutical Sciences, Karachi University, Pakistan, 2021.
19. Syeda Najam Zehra1, Ishrat Younus1, Saima Mahmood Malhi2, Muhammad Liaquat Raza3, Azfar Athar Ishaqui4, Sana Khan. Effect of Adenosine A2a receptor antagonist in haloperidol induced model of Parkinson’s disease. Research Square, 2021.
