Dr. Moona Mehboob Khan

Research

International Book
In-vitro and in-vivo interaction studies of leflunomide, Lambert Academic Publishing, year 2013.

1    Effect of Leflunomide–Metal Complexes on ROS, TNF, and Brain Indolamines in Comparison with Anti-Depressants as Adjunct Therapy in Rheumatoid Arthritic Model, Almas Naeem, Noor Jahan , Moona Mehboob Khan , Ghulam Abbas, Faheema Siddiqui, Muhammad Usaid Khalid and Waqas Ahmed Farooqui, Biomedicines 2023, 11, 2214.https://doi.org/10.3390/biomedicines11082214

2.    Effects of ciprofloxacin or co-amoxicillin with and without antidepressants on behavioral deficit in rats induced with chronic suppurative otitis media.- Mehjabeen , Kashif Mehboob Khan , Shafaque Mehboob, Moona Mehboob , Tariq Khan , Sm Tariq Rafi , Noor Jahan , Asma Wazir , Farah Owais. Pak J Pharm Sci. 2021 Sep;34(5(Supplementary)):1945-1949.
3.    Spectroscopic interaction studies of H2 receptor antagonists with levocetirizine. Shafaque Mehboob , Moona Mehboob , Darakshan M Saleem , Mehjabeen , S M Tariq Rafi , Hurtamina Khan , Noor Jahan , Farah Owais , Fakhra Batool , Najma Sultana  Pak J Pharm Sci. 2021 May;34(3(Special)):1283-1287

4.    Spectroscopic interactions of non-insulin-dependent diabetes mellitus with levocetirizine. Shafaque Mehboob , Moona Mehboob, - Mehjabeen, S M Tariq Rafi , Tariq Khan, Humaira Anser, Shaheen Perveen , Noor Jahan, Asma Wazir, Farah Owais. Pak J Pharm Sci. 2021 Jul;34(4(Supplementary)):1639-1644
 5.         Hepatotoxicity induced by chronic suppurative otitis media in rats and effects of ceftazidime and amikacin on it. Shafaque Mehboob , Darakhshan M Saleem , - Mehjabeen , Moona Mehboob , Noor Jahan, Shaheen Perveen , S M Tariq Rafi , Humaira Anser , Farah Owais. Pak J Pharm Sci. 2021 May;34(3(Special)):1243-1248.
7.        Effects of ceftazidime with and without imipramine and bromazepam on behavior and neuro-inflammatory parameters in rats with chronic suppurative otitis, Shafaque Mehboob, SM Tariq Rafi, Mehjabeen, Moona Mehboob, Darakshan Saleem, Hassan Ahmed,  Pakistan Journal of Pharmaceutical Sciences 2020 33(3):1271-1276. Impact Factor 0.596.
8.        Pharmacological effects of oral vitamin D intake on pulmonary function Test and Interleukin-17 in adult asthmatic patients in Karachi, Afshan Mehboob, Durr-e-Sameen, Meraj Rahim, Sumera Mustafa, Moona Mehboob Khan and Anwar Ali, doi.org/10.36721/PJPS.2020.33.2.SUP.751-754.1. Impact Factor 0.596.

9,        Inhibition of diet-restriction-induced behavioral deficits by tryptophan administration in rats Saleem DM, Mehboob S, Khan MM, Samad N, Zafar A, Haleem DJ Pak J Pharm Sci. 2018 May;31(3(Supplementary)):1021-1029. Impact Factor 0.596.

10.     Determination of tryptophan in raw materials, rat brain and human plasma by RP-HPLC technique,  Najma Sultana, M Saeed Arayne, Moona Mehboob Khan, Darakhshan M Saleem, Agha Zeeshan Mirza, Journal of chromatographic science 04/2012; 50(6): 531-7.  Impact factor 1.216, Citation 6.

11    Development and Validation of a Liquid Chromatographic Method for the determinationof Leflunomide: Application to In Vitro Drug Metal Interactions” Sultana Najma, Arayne M. Saeed, Khan Moona Mehboob*and  Nawaz. M, (2011) Chinese journal of chemistry, 29(9) 1933-1938. Impact Factor 2.376.

12     High Performance Liquid Chromatography Assay for Moxifloxacin in Bulk, Pharmaceutical Formulations and Serum: Application to In-vitro Metal Interaction”, N Sultana, MS Arayne, Mahwish Akhtar, S Shamim, S Gul and MM Khan (2010), Journal of the Chinese Chemical society, 57, 708-717. Impact Factor 1.188.

13    Development of Liquid Chromatography–UV Method for Simultaneous Determination of Lefunomide and Four NSAIDs in API and Pharmaceutical Formulations: Its Aapplication to In-vitro Interaction Studies, Sultana N, Arayne MS, Khan MM, Ali SN, Medicinal Chemistry. 01/2013; 3(3):262-270.

14    Simultaneous effect of leflunomide with imipramine and fluoxetine in carrageenan induced acute arthritic model jahan N, KHAN MM, NAEEM A, ASLAM F, MEHJABBEN,IJBPAS, April, 2018, 7(4): 548-557, Impact Factor 1.318.

15    Role of tryptophan in the pathogenesis of hepatic encephalopathy, Darakhshan M. Saleem, Saida Haider, Moona M. Khan, Tahir Shamsi, Darakhshan J. Haleem, (2008) Journal of Pakistan Medical Association, 58(2), 68-70. Impact Factor 0.414.

16    Synthesis, Characterization and Anti-Inflammatory Activity of Metal Complexes of 5-Methyl-N-[4-(Trifluoromethyl) Phenyl]-Isoxazole-4-Carboxamide on Carrageenan Induced Arthritic Rats” Najma Sultana, M. Saeed Arayne, Moona Mehboob Khan and M. Afzal, JSM Chemistry, Vol 2 (1), 2014: 1006.

17    Leflunomide with Meloxicam on Progression of Rheumatoid Arthritis and its Associated Depression in AIA Rats, Arayne MS, Sultana N, Khan MM, Simjee SU, Clinical Pharmacology and Biopharmaceutics. 01/2014; 3(1000114):p 1000114.

18    In vivo Interaction Studies of ACE Inhibitors with NSAIDs on Carrageenan Induced Inflammation, Safila Naveed, Najma Sultana, Saeed Arayne M, Rakhshinda Siddiqui, Moona Mehboob, Clinical Pharmacology & Biopharmaceutics. 02/2013; 2(1):1000108.

19    Decreased Serotonin Level in Adjuvant Induced Arthritic rats, Khan M, Sultana N, Arayne MS, Darakhshan MS, International J of Toxicology and Pharmacology Research. 01/2011; 3(3):9-13.

20    Altered brain monoamines metabolism in Thioacetamide Induced hepatic encephalopathy in rats”, Darakhshan M Saleem, Saida Haider, Moona.M. Khan, Shafaque M.Khan,Uzma Rahim, Shafia Tabassum, Darakhshan. J.Haleem (2013) International journal of toxicology and pharmacology research.

21    Drug-Drug Interaction Studies of Levocetirizine with Atenolol ,Shafaque Mehboob, Muhammad Azhar Mughal, Khalid Aftab, Moona Mehboob Khan, Najma Sultana, Syed Arayne, Journal of Pharmacy and Pharmacology , 2017,Volume 5; doi:10.17265/2328-2150/2017.03.002.

22    Spirometric Evaluation of  Asthmatic Children and its association with Biophysical Parameters: A Case Control Study, Afshan Mehboob Khan, Sumera Mustafa Abbasi, Fareena Khalil, Darakhshan M Saleem,  Moona.M. Khan and  Shafaque M.Khan,  Annals of Jinnah Sindh Medical University, 2017,  volume 3(1), page number 14.

23    Behavorial Response to Apomorphine in Diet Restriction Induced Hyperactivity in Rats, Khalid Aftab, Darakhshan M Saleem, Moona.M. Khan, Shafaque Mehboob, Shafia Tabassum, Darakhshan. J.Haleem, Journal of Pharmacy and Pharmacology , 2017, Volume 1(2) doi:10.17265/2328-2150/2017.03.002.