Dr. Mahwish Akhtar

Qualifications

•   Ph.D.     UNIVERSITY OF KARACHI    2006-2011
•    B Pharm. (GPR- 2.96)    UNIVERSITY OF KARACHI    2000-2004
•    HSC (GRADE-B )    SIR SYED GOVT. GIRLS COLLEGE    1997-1999
•    SSC (GRADE- A)    GOVT. GIRLS FARHANA SCHOOL    1994-1996

Experience

 Assistant Professor (BPS 19)    Dow College Of Pharmacy, D.U.H.S. Karachi    15-07-2011 till date

Research

 BOOK PUBLICATIONS:
Mahwish Akhtar, Interaction of Moxifloxacin, LAMBERT Academic Publishing, 2012
ABSTRACT PUBLICATIONS:
1.    S Shamim, Mahwish Akhtar, S Shamim, Use of Magnetic Resonance Spectroscopy (MRS) as a Tool for Weight Reduction, 19 international Pharmacy Conference & Exhibition (IPCE 2016), PC hotel, Lahore, Pakistan, 21st -24th April 2016.  
2.    Mahwish Akhtar, N Sultana, MS Arayne, S Gul, S Shamim, Simultaneous Determination of Moxifloxacin with Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) In Bulk, Dosage Formulations and Serum by RP-HPLC: Application to In-Vitro Drug Interactions, 3rd National Computational Sciences Conference (NCSC 2015), at Islamabad, May 13-15, 2015.
3.    S Shamim, N Sultana, MS Arayne, S Gul, Mahwish Akhtar, Synthesis, Characterization, Antibacterial and antifungal activities of Gemifloxacin-metal complexes, 1st International Conference on Recent Innovations in Pharmaceutical Sciences (ICRIPS-2015) at Islamabad, 3-5 March.
4.    Mahwish Akhtar, N Sultana, MS Arayne, S Gul, S Shamim, Simultaneous Determination of Moxifloxacin with Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) In Bulk, Dosage Formulations and Serum by RP-HPLC: Application to In-Vitro Drug Interactions, Fourth Pre-Faculty Research Day Workshop, DUHS, 14 & 15 January, 2013
5.    S Shamim, Mahwish Akhtar, S Gul, Comparative In-Vitro Antibiotic Activity of Fluoroquinolones with Macrolides, Fourth Pre-Faculty Research Day Workshop, DUHS, 14 & 15 January, 2013
6.    Mahwish Akhtar, U Farwa, I Ali, S Hassan, H A Siddique, H Amin Sunshine vitamin deficiency despite abundant sun exposure, Golden Jubilee Cerebration theme: Post Graduate Medicinal Education of Physicians & surgeons Pakistan. 9th -11th Nov, 2012
7.    Mahwish Akhtar, U Farwa, I Ali, S Hassan, H A Siddique, H Amin, Sunshine vitamin deficiency despite abundant sun exposure, 1st National Conference on Pharmacy Profession, Dow University of Health Sciences, Karachi, Pakistan, 2nd  – 3rd  May, 2012
8.    S Gul, N Sultana, MS Arayne, S Shamim, Mahwish Akhtar, New Method for optimization and Simultaneous Determination of Sparfloxacin and Non Stroidal Anti inflammatory drugs: it’s invitro Application, 3rd Symposium on Pharmacist: Aneed of Health Care System, Karachi. 28th April 2012.
9.    Mahwish Akhtar, N Sultana and MS Arayne Simultaneous Determination of Moxifloxacin with NonSteroidal Anti-Inflammatory Drugs (NSAIDs) In Bulk, Dosage Formulations and Serum by RP-HPLC: Application to In-Vitro Drug Interactions. 3rd International Symposium cum Training Course on Molecular Medicine and Drug Research Karachi (MMDR) Karachi. 3-6 January, 2011.
10.    Mahwish Akhtar, N Sultana and MS Arayne Synthesis, Characterization and Antibacterial Studies of 1-cyclopropyl-7-[(s,s)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-1,4-dihydro-4-oxo3quinoline Carboxylic Acid with Antacids. 1st International Conference of Chemistry and its Role Science (ICCRS-1), Karachi. 3-5 January, 2011.
11.    Mahwish Akhtar, N Sultana and MS Arayne Simultaneous Determination of Moxifloxacin with NonSteroidal Anti-Inflammatory Drugs (NSAIDs) In Bulk, Dosage Formulations and Serum by RP-HPLC: Application to In-Vitro Drug Interactions. 1st International Conference of Chemistry and its Role Science (ICCRS-1), Karachi. 3-5 January, 2011.
12.    S Gul, S Shamim, Mahwish Akhtar, MM Khan and S Naveed Comparative in-vitro Antibacterial Activity of Fluoroquinolones and Macrolides. 5th Pharmacognosy Conference 2010 on Current Challenges in Medicine and Therapy. Karachi 10th July 2010.
13.    Mahwish Akhtar, N Sultana and MS Arayne Synthesis, Characterization and Antibacterial and Antifungal Studies of Moxifloxacin with NSAIDs. 19th National Chemistry Conference 2009, Kohat. June 9-11, 2009.
14.    Mahwish Akhtar, N Sultana and MS Arayne Synthesis, Characterization and Antibacterial Studies of Moxifloxacin with H2 Receptor Antagonists. 2nd International Symposium cum Training Course on Molecular Medicine and Drug Research Karachi, 12-15 January, 2009.
15.    Mahwish Akhtar, N Sultana and MS Arayne Synthesis, Characterization and Antibacterial Studies of 1-cyclopropyl-7-[(s,s)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-1,4-dihydro-4-oxo3quinoline Carboxylic Acid with Various Aromatic Amines. 1st National Symposium on Analytical, Environmental and Applied Chemistry, Khairpur. 24-25 October, 2008.
16.    N Sultana, MS Arayne and Mahwish Akhtar Synthesis, Characterization and Antibacterial Studies of 1-cyclopropyl-7-[(s,s)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-1,4-dihydro-4-oxo3quinoline carboxylic acid with Various Aliphatic and Aromatic Amines, Amides and Phenol. 17th International Conference on Organic Synthesis Daejeon, Korea. 22-27 June, 2008.
17.    N Sultana, MS Arayne and Mahwish Akhtar Synthesis, Characterization and Antibacterial Studies of 1-cyclopropyl-7-[(s,s)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-1,4-dihydro-4-oxo3quinoline Carboxylic Acid with Essential and Trace Elements. 18th National Chemistry Conference. Lahore. 25-27 February, 2008.
18.    N Sultana, MS Arayne and Mahwish Akhtar Synthesis, Characterization and Antibacterial Studies of 1-cyclopropyl-7-[(s,s)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-1,4-dihydro-4-oxo3quinoline carboxylic acid. 11th International Symposium on Natural Product Chemistry (11th ISNPC) Karachi, Pakistan. January 3-6, 2008.
PAPER PUBLICATIONS IN INTERNATIONAL JOURNALS
1.    N Sultana, MS Arayne, Mahwish Akhtar, S Shamim, S Gul and MM Khan (2010) High Performance Liquid Chromatography Assay for Moxifloxacin in Bulk, Pharmaceutical Formulations and Serum: Application to In-vitro Metal Interaction, Journal of the Chinese Chemical Society, 57, 708-717.
2.    N Sultana, S Shamim, Mahwish Akhtar, S Gul and MS Arayne (2010) Simultaneous determination of Gemifloxacin and diuretic in bulk, pharmaceutical formulation and human serum by RP-HPLC, Quimica Nova, 33, 1590-1593.
3.    N Sultana, Mahwish Akhtar, S Shamim, S Gul, and MS Arayne (2011) Simultaneous Determination of Moxifloxacin and H2 Receptor Antagonist In Pharmaceutical Dosage Formulations By RP-HPLC: Application To In-Vitro Drug Interactions, Quimica Nova, Vol. 34, 683-688
4.    N Sultana, MS Arayne, S Gul, Mahwish Akhtar and S Shamim (2011) Simultaneous Determination of Sparfloxacin and Commonly Used H2 Receptor Antagonists by Rp-HPLC: Application to In-Vitro Drug Interactions, Medicinal Chemistry Research, DOI10.1007/s00044-011-9586-4
5.    N Sultana, MS Arayne, S Shamim, Mahwish Akhtar and S Gul (2011) Validated Method for the Determination of Gemifloxacin in Bulk, Pharmaceutical Formulations and Human Serum by RP-HPLC; In-vitro Applications, Journal of the Brazilian Chemical Society, Vol. 22, 987-992
6.    S Gul, N Sultana, MS Arayne, S Shamim, and Mahwish Akhtar (2012) New Method for Optimization and Simultaneous Determination of Sparfloxacin and Non Steroidal Anti-Inflammatory Drugs: Its In-Vitro Application, American Journal of Analytical Chemistry, Vol. 3 (4), 328-337  DOI: 10.4236/ajac.2012.34045
7.    S Shamim, N Sultana, M S Arayne, Mahwish Akhtar and S Gul (2012) Optimization and simultaneous determination of gemifloxacin and Non-steroidal anti-inflammatory drugs in bulk, pharmaceutical formulations and human serum by RP-HPLC and its applications, International Research Journal of Pharmacy and Pharmacology (ISSN 2251-0176) Vol. 2(10)
8.    S Naveed, N Sultana, S M Arayne and Mahwish Akhtar (2013) In-vivo interaction studies of captopril with flurbiprofen and ibuprofen on carrageenan induced inflammation, Open Access Scientific Reports, Vol 2, (12), 1-3.
9.    S Gul, N Sultana, M. S Arayne, S Shamim, Mahwish Akhtar and A Khan (2013) Sparfloxacin-Metal Complexes as Urease Inhibitors: their Synthesis, Characterization, Antimicrobial and Anti-Enzymatic Evaluation, journal of chemistry, Vol 2013, 12.
10.    S Gul, N Sultana, M S Arayne, S Shamim, and Mahwish Akhtar (2013) Sparfloxacin Determination In Bulk Materials, Pharmaceutical Formulations and Human Serum by Reverse Phase HPLC Method, African Journal of pharmacy and Pharmacology, Vol 7 (30) 2131-2139.
11.    N sultana, M. S Arayne, Mahwish Akhtar (2014) Synthesis and Antimicrobial Chattels of 1-Cyclopropyl- 7-[(S,S)-2,8-Diazabicyclo [4.3.0]Non-8-Yl]-6-Fluoro-8- Methoxy-1,4-Dihydro-4-Oxo- 3-Quinolinecarboxylic Acid Metal Complexes of Biological Interest, JSM Chemistry, Vol 2(1) 1007.
12.    Rubina M., Sana S., Najma S., M. Saeed A. and Mahwish Akhtar, (2018) Rp-Hplc Method for The Simultaneous Estimation of Lisinopril and Diuretics In Bulk, Dosage Forms and Human Serum, IJBPAS, 7(12): 2005-2016
13.    Mahwish Akhtar, N Sultana, MS Arayne, TA Siddiqi, A Khan, (2019) Synthesis, characterization, antimicrobial and enzyme inhibitory studies of moxifloxacin with aromatic carboxylic acids, Pakistan Journal of Pharmaceutical Sciences, 32(3(suppl)): 1201-1206.
14.    Mahwish Akhtar, N Sultana, MS Arayne, TA Siddiqi, A Khan, (2019) Moxifloxacin-Ester derivatives: Synthesis, characterization and pharmacological evaluation, Pakistan Journal of Pharmaceutical Sciences, 32(3(special)): 1301-1306.
15.    Mahwish Akhtar, TA Siddiqi, S Inayat, S A Hassan, S Naz, (2019) Physicochemical, Pharmacokinetic and Toxicological Evaluation of 1-cyclopropyl-6-fluoroN'-isonicotinoyl-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carbohydrazide: An in-Silico Approach. IJBPAS, May, 2019, 8(5): 992-1002.
16.    Mahwish Akhtar, S Shamim, TA Siddiqi, N Sultana, MS Arayne, (2019) Synthesis and Antimicrobial Evaluation of Unique 3-Carboxamide Derivatives of Moxifloxacin with Selected H2 Inhibitor, IJBPAS, May, 2019, 8(5): 968-980.
17.    S Shamim, S Gul, Mahwish Akhtar, I Begum, H Ashraf (2021) synthesis, characterization, invitro bacterial, fungal and enzymatic activities of C-7 Modified Gemifloxacin Analogs, IJBPAS, June 2021 10(6): 1733-1745.
18.    Mahwish Akhtar, S Gul, S Shamim, (2021) Simultaneous Determination of Moxifloxacin with Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) In Bulk, Dosage Formulations and Serum by RP-HPLC: Application to In-Vitro Drug Interactions, Pakistan Journal of Pharmaceutical Sciences 34 (6) 2091-2099.
19.    Mahwish Akhtar, S Shamim, (2021) Development of potent Remdesivir Derivative against SAR-CoV-2 protease inhibitors: Design, Modification, Molecular Modeling and Molecular Dynamics Simulations, Pakistan Journal of Pharmaceutical Sciences 34 (3) SUP.1119-1126.1.
20.    Zuneera Akram, Rehana Perveen, Saima Saleem, Mahwish Akhtar, Hina Abrar, Rubina Siddiqui, Muzammil Hussain, Usman Ghani Faqooqi, Shumaila Pervaiz, (2021)  In-Vitro and In Silico Antiplatelet Action of the New Piperidin4-One-Thiosemicarbazide Derivative, (Annals of R.S.C.B.), Vol. 25, Issue 6, 2021, pp. 20257 – 20266.
21.    Rubina Siddiqui, Shamim Akhtar, Shazia Haider, Zafar Saied Saify, Mahwish Akhtar and Sana Shamim, (2021) New series of hydrazinyl thiazole derivatives of piperidin-4-one:Synthesis, structural elucidation, analgesic activity and comparative structure activity relationship, Pak. J. Pharm. Sci., Vol.34, No.4, July 2021, pp.1415-1420.
22.    Mahwish Akhtar, NoorJahan, M Imran, Salman Asheaq Ahmed, Sara Naqvi, Syed Huzaifa Shah, Development of potent SARS-CoV 3CL protease inhibitors: in-silico Analogues Designing of Darunavir, Molecular Modelling and Molecular Dynamic Simulation, Asian Journal of Chemistry, Vol. 34 (9), 2343-2350.
23.    FM Khan, S Naeem, S Usmani, Mahwish Akhtar, S Akhtar, W Gul, Virtual Screening, Molecular Docking Study, Characterization, And In-Vitro Antibacterial Evaluation of Piperazine Derivatives, RADS Journal of Pharmacy and Pharmaceutical Sciences,  Vol 10 No 4 (2022).