Dr. Sobia Ekram

Research

2024:
1. Sobia Ekram, Shumaila Khalid, Faiza Ramzan, Asmat Salim, MC Durrieu and Irfan Khan. “Extracellular
Vesicles Derived from Human Umbilical Cord-Mesenchymal Stem Cells Ameliorate Intervertebral Disc
Degeneration. Submitted to Frontiers in Bioengineering and Biotechnology, 2024 Oct.

2. Ramzan F, Khalid S, Ekram S, Salim A, Frazier T, Begum S, Mohiuddin OA, Khan I. 3D bio scaffold support
osteogenic differentiation of mesenchymal stem cells. Cell Biol Int. 2024 May;48(5):594-609. [DOI:

10.1002/cbin.12131, PMID: 38321826].
2023:
3. Ekram S, Khalid S, Ramzan F, Salim A, Bashir I, Durrieu MC, Khan I. Mesenchymal Stem Cell-Derived
Extracellular Vesicles Protect Rat Nucleus Pulposus Cells from Oxidative Stress. Cartilage. 2023 May
4:19476035231172154. [DOI: 10.1177/19476035231172154, PMID: 37139781]

4. Khalid S, Ekram S, Ramzan F, Salim A, Khan I. Co-regulation of Sox9 and TGFβ1 transcription factors in
mesenchymal stem cells regenerated the intervertebral disc degeneration. Front Med (Lausanne). 2023 Mar
17;10:1127303. [DOI: 10.3389/fmed.2023.1127303. PMID: 37007782]

5. Ekram, S., Rajput, S. N., Khalid, S., Ramzan, F., Salim, A., & Khan, I. Pain and Inflammation Profile of a
Degenerated Intervertebral Disc. Molecular Medicine Communications, 2023 Jan:2(02), 101-119. [DOI:
10.55627/mmc.002.002.0157]
2022:
6. Ramzan F, Ekram S, Frazier T, Salim A, Mohiuddin OA, Khan I. Decellularized Human Umbilical Tissue-
Derived Hydrogels Promote Proliferation and Chondrogenic Differentiation of Mesenchymal Stem Cells.
Bioengineering (Basel). 2022 May 30;9(6):239. [DOI: 10.3390/bioengineering9060239, PMID: 35735483]

7. Khalid S, Ekram S, Salim A, Chaudhry GR, Khan I. Transcription regulators differentiate mesenchymal stem
cells into chondroprogenitors, and their in vivo implantation regenerated the intervertebral disc degeneration.
World J Stem Cells. 2022 Feb 26;14(2):163-182. [DOI: 10.4252/wjsc.v14.i2.163, PMID: 35432734]
2021:
8. Ekram S, Khalid S, Salim A, Khan I. Regulating the fate of stem cells for regenerating the intervertebral disc
degeneration. World J Stem Cells. 2021 Dec 26;13(12):1881-1904. [DOI: 10.4252/wjsc.v13.i12.1881, PMID:
35069988]
9. Ekram S, Khalid S, Bashir I, Salim A, Khan I. Human umbilical cord-derived mesenchymal stem cells and
their chondroprogenitor derivatives reduced pain and inflammation signaling and promote regeneration in a
rat intervertebral disc degeneration model. Mol Cell Biochem. 2021 Aug;476(8):3191-3205. [DOI:
10.1007/s11010-021-04155-9, PMID: 33864569]
2020:

10. Ekram, S., Ali, S. R., Salim, A., & Khan, I. “Role of gold-and silver-based nanoparticles in stem cells

differentiation. In Metal Nanoparticles for Drug Delivery and Diagnostic Applications”. Elsevier. 2020 (pp.
99-118). [DOI: 10.1016/B978-0-12-816960-5.00007-0]