Dr. Talat Roome

Research

2024:

Kawish, M., Ullah, S., Roome, T., Razzak, A., Aslam, S., & Raza Shah, M. (2024). Thermoresponsive lipids engineered magnetic nanoparticles for spatiotemporal delivery of hesperidin to inflammatory sites in animal model. Pharmaceutical Development and Technology, 29(7), 762-775. [doi: 10.1080/10837450.2024.2393216]

2023:

• Hasnain, M., Kanwal, T., Rehman, K., Rehman, S. R. U., Aslam, S., Roome, T., & Shah, M. R. Microarray needles comprised of arginine-modified chitosan/PVA hydrogel for enhanced antibacterial and wound healing potential of curcumin. International Journal of Biological Macromolecules.2023;253(1)126697. [doi:10.1016/j.ijbiomac.2023.126697].

  • The impact factor is 8.2 and HEC category “W”

• Ullah, A., Mamun, A. A., Zaidi, M. B., Roome, T., & Hasan, A. A calcium peroxide incorporated oxygen releasing chitosan-PVA patch for Diabetic wound healing. Biomedicine & pharmacotherapy. 2023, 165, 115156. [doi:10.1016/j.biopha.2023.115156].

  • The impact factor is 7.5 and HEC category “W”

• Hasan A, Roome T, Wahid M, Ansari SA, Khan JA, Kiyani A, Jilani SN. A novel experimental model to investigate fungal involvement shows expression of Dectin‐1 in periapical lesion pathogenesis. Journal of Oral Rehabilitation. 2023 June 1;50 (8). [doi:10.1111/joor.13528]

  • The impact factor is 3.558 and HEC category “W”

• Jabri T, Roome T, Razzak A, Aziz S, Imran M, Sikandar B, Elhissi A, Aslam SM, RazaShah M. Fabrication of hesperidin hybrid lecithin-folic acid silver nanoparticles and its evaluation as anti-arthritis formulation in autoimmune arthritic rat model. Journal of Molecular Structure. 2023 Mar 15;1276:134722. [doi:10.1016/j.molstruc.2022.134722]

• • The impact factor is 3.841 and HEC category “W”

• Hasan A, Roome T, Wahid M, Ansari SA, Khan JA, Jilani SN, Jawed A, Kiyani A. Expression of Toll-like receptor 2, Dectin-1, and Osteopontin in murine model of pulpitis. Clinical Oral Investigations. 2023 Mar;27(3):1177-92. [doi: 10.1007/s00784-022-04732-2]

  • The impact factor is 3.606 and HEC category “W”

2022:

• Hasan A, Roome T, Wahid M, Ansari SA, Akhtar H, Jilani SN, Kiyani A. Gene expression analysis of toll like receptor 2 and 4, Dectin-1, Osteopontin and inflammatory cytokines in human dental pulp ex-vivo. BMC Oral Health. 2022 Dec;22(1):1-5. [doi: 10.1186/s12903-022-02621-4]

  • The impact factor is 3.747 and HEC category “W”

• Aslam Z, Roome T, Razzak A, Aslam SM, Zaidi MB, Kanwal T, Sikandar B, Bertino MF, Rehman K, Shah MR. Investigation of wound healing potential of photo-active curcumin-ZnO-nanoconjugates in excisional wound model. Photodiagnosis and Photodynamic Therapy. 2022 Sep 1;39:102956. [doi: 10.1016/j.pdpdt.2022.102956]

  • The impact factor is 3.577 and HEC category “X”

2021:

• Roome T, Qasim M, Aziz S, Farooq AD, Razzaq A, Ali SF. Assessment of acute, sub-acute, chronic and genotoxicity of polyherbal formulation DCD-684 in mice. Pak. J. Pharm. Sci. 2021 Jul 1;34(4):1485-98. [PMID: 34799324]

  • The impact factor is 0.863 and HEC category “Y”

• Roome T, Qasim M, Farooq AD, Ilyas Q, Aziz S, Ali SF. Antispasmodic activity and mechanism of action of polyherbal formulation DCD-684 on rabbit jejunum. Pakistan Journal of Pharmaceutical Sciences. 2021 Mar 2;34. [PMID: 34275806]

  • The impact factor is 0.863 and HEC category “Y”

• Kanwal T, Saifullah S, ur Rehman J, Kawish M, Razzak A, Maharjan R, Imran M, Ali I, Roome T, Simjee SU, Shah MR. Design of absorption enhancer containing self-nanoemulsifying drug delivery system (SNEDDS) for curcumin improved anti-cancer activity and oral bioavailability. Journal of molecular liquids. 2021 Feb 15;324:114774. [doi: 10.1016/j.molliq.2020.114774]

  • The impact factor is 6.633 and HEC category “W”

2019:

• Roome T, Aziz S, Razzak A, Aslam Z, Jamali KS, Sikandar B, Fatima T, Abidi L, Imran M, Faizi S, Shah MR. Opuntioside, opuntiol and its metallic nanoparticles attenuate adjuvant-induced arthritis: novel suppressors of toll-like receptors-2 and-4. Biomedicine & Pharmacotherapy. 2019 Apr 1;112:108624. [doi: 10.1016/j.biopha.2019.108624]

  • The impact factor is 7.419 and HEC category “Y”

2018:

• Imran M, Hameed A, Shafiullah, Hafizur RM, Ali I, Roome T, Shah MR. Fabrication of Xanthan stabilized green gold nanoparticles based tolbutamide delivery system for enhanced insulin secretion in mice pancreatic islets. Journal of Macromolecular Science, Part A. 2018 Dec 2;55(11-12):729-35. [doi: 10.1080/10601325.2018.1510290]

  • The impact factor is 2.216 and HEC category “Y”

• Rao K, Roome T, Aziz S, Razzak A, Abbas G, Imran M, Jabri T, Gul J, Hussain M, Sikandar B, Sharafat S. Bergenin loaded gum xanthan stabilized silver nanoparticles suppress synovial inflammation through modulation of the immune response and oxidative stress in adjuvant induced arthritic rats. Journal of Materials Chemistry B. 2018;6(27):4486-501. [doi: 10.1039/c8tb00672e]

  • The impact factor is 7.0 and HEC category “W”

• Rao K, Aziz S, Roome T, Razzak A, Sikandar B, Jamali KS, Imran M, Jabri T, Shah MR. Gum acacia stabilized silver nanoparticles based nano-cargo for enhanced anti-arthritic potentials of hesperidin in adjuvant induced arthritic rats. Artificial cells, nanomedicine, and biotechnology. 2018 Oct 31;46(sup1):597-607. [doi: 10.1080/21691401.2018.1431653]

  • The impact factor is 6.355 and HEC category “W”

2017:

• Zaman N, Ahmad H, Ali Abid M, Roome T, Abbas G. Acetaminophen (paracetamol) facilitated extinction learning in contextual fear conditioned rats. Letters in Drug Design & Discovery. 2017 Aug 1;14(8):898-903. [doi: 10.2174/1570180814666170203162557]

  • The impact factor is 1.099 and HEC category

PATENTS:

• Polyacrilonytrile Based Electrospun Nanofibers Loaded with Zinc Oxide Quercetin Nanoparticles for Wound Healing. Raza Shah, Tooba Jabri, Kanwal Iqbal, Talat Roome, Shafi Ullah, Qamar Khan. Publication No: US 2023/0181371 A1. June 15 2023