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Prof. Dr. Muhammad Asif Qureshi

Name

Prof. Dr. Muhammad Asif Qureshi

Designation

Professor / Administrative Title: Director Medical Lab, DDRRL

Email

a.qureshi@duhs.edu.pk

Office

Department of Pathology, DIMC, Ojha Campus, Dow University of Health Sciences Karachi

Qualifications

  • MBBS (Dow)
  • PhD (Glasgow)
  • Postdoc (Germany)
  • M.A (I.R)
  • CHPE

Research

Cancer Immunology, Molecular Pathology, Molecular Carcinogenesis, Cancer Epidemiology, Personalized Medicine

⦁ ResearchGate/ORCID link: ⦁ orcid.org/0000-0002-8370-1069 ⦁ List of Selected Research Publications (with DOI citation)

PEER REVIEWED PUBLICATIONS

  1. Syed SA, Qureshi MA, Khan S, Kumar R, Khyani IAM, Knan BA, Safdar J. Differential Regulation of Innate Lymphoid Cells in Human & Murine Oral Squamous Cell Carcinoma. Int. J. Mol. Sci 24(2):1627. doi:10.3390/ijms24021627, 2023. (PMID: 36675138)
  2. Zhang H, Qureshi MA, Wahid M, Charifa A, Ehsan A, Ip A, De Dios I, Ma W, Sharma I, McCloskey J, Donato M, Siegel D, Gutierrez M, Pecora A, Goy A, Albitar M. Differential Diagnosis of Hematologic and Solid Tumors Using Targeted Transcriptome and Artificial Intelligence. Am J Pathol. 193(1):51-59. doi: 10.1016/j.ajpath.2022.09.006, 2023. (PMID: 36243045)
  3. Pervez S, Jabbar AA, Haider G, Qureshi MA, Ashraf S, Lateef F, Khurshid M, Bashir I, Zaidi M, Mushtaq N, Fadoo Z, Quraishy MS, Yaqoob N, Alam E, Qureshi H. Karachi Cancer Registry (KCR): Consolidated Data of 5-years 2017-2021. J Coll Physicians Surg Pak 33(5):560-565. doi: 10.29271/jcpsp.2023.05.560, 2023. (PMID: 37190693)
  4. Iqbal S, Khan S, Qureshi MA, Sayeed MA, Khan BA, Zaheer S, Faruqui H, Rajput AW. Clinical and Biochemical Characteristics of COVID-19 Patients During the Delta-Omicron Wave with Risk Assessment of Adverse Outcomes. J Coll Physicians Surg Pak 33(3):297-302. doi: 10.29271/jcpsp.2023.03.297., 2023. (PMID: 36945160)
  5. Ahmed S, Khan S, Qureshi MA, Bukhari U, Anis M, Mughal MN. Expressional variations of Kaiso: an association with pathological characteristics and field cancerization of OSCC. BMC Cancer 17;22(1):990. doi: 10.1186/s12885-022-10014-7, 2022. (PMID: 36115941)
  6. Ahmad R, Riaz M, Aldholmi M, Qureshi MA, Uddin S, Bhat AA, Poyil P, Baig M, Pourahmad J, Ganesan T, Khan AQ, Siddiqui Z, El-Demellawy M, Gholamalizadeh M, Purnomosari D, Salim EI, Mousavi Jarrahi SZ, Zhang JY, Mohammad Nejad S, Mosavi Jarrahi A. Development of a Critical Appraisal Tool (AIMRDA) for the Peer-Review of Studies Assessing the Anticancer Activity of Natural Products: A Step towards Reproducibility. Asian Pac J Cancer Prev 22(12):3735-3740. doi: 10.31557/APJCP.2021.22.12.3735, 2022. (PMID: 34973682)
  7. Syed SA, Qureshi MA, Khan S, Kumar R, Shafique Y, Khan BA, Safdar J. Development of a murine model of oral carcinogenesis: an accelerated tool for biomarker and anti-tumour drug discovery. Ecancermedicalscience 15;16:1413. doi: 10.3332/ecancer.2022.1413, 2022. (PMID: 36072235)
  8. Kumari P, Syed SA, Wahid M, Qureshi MA, Kumar R. Expression of miR-31 in saliva-liquid biopsy in patients with oral squamous cell carcinoma. J Taibah Univ Med Sci 16(5):733-739. doi: 10.1016/j.jtumed.2021.03.007, 2022. (PMID: 34690655)
  9. Qureshi MA, Syed SA, Sharafat S. Lip and oral cavity cancers (C00-C06) from a mega city of Pakistan: Ten-year data from the Dow Cancer Registry. J Taibah Univ Med Sci. 16(4):624-627. doi: 10.1016/j.jtumed.2021.02.001, 2021. (PMID: 34408617)
  10. Shafique Y, Qureshi MA, Khan S, Mirza T. Differential Immune Landscape of Hepatocellular Carcinoma Suggests Potential role of Macrophages in Hepatocarcinogenesis. Pak J Med Sci 37(3):858-862. doi: 10.12669/pjms.37.3.2973, 2021. (PMID: 34104178)
  11. Qureshi MA. Revival of Cancer Registration in Karachi, Pakistan. Asian Pac J Cancer Prev 1;22(1):1. doi: 10.31557/APJCP.2021.22.1.1, 2021. (PMID: 33507671)
  12. Rehman SH, Majid B, Syed SA, Qureshi MA. Quantitative Analyses of Skin Cancer Research in Pakistan. Pak J Med Sci. 37(2):582-587. doi: 10.12669/pjms.37.2.2889, 2021. (PMID: 33679954)
  13. Qureshi MA, Khan S, Tauheed MS, Syed SA, Ujjan ID, Lail A, Sharafat S. Pan-Cancer Multiomics Analysis of TC2N Gene Suggests its Important Role(s) in Tumourigenesis of Many Cancers. Asian Pac J Cancer Prev. 21(11):3199-3209. doi: 10.31557/APJCP.2020.21.11.3199, 2020. (PMID: 33247676)
  14. Pervez S, Jabbar AA, Haider G, Ashraf S, Qureshi MA, Lateef F, Bashir I, Zaidi M, Khurshid M, Quraishy MS, Siddiqi T, Rizwan U, Saqib MAN, Memon MA, Alam E, Qureshi H. Karachi Cancer Registry (KCR): Age-Standardized Incidence Rate by Age-Group and Gender in a Mega City of Pakistan. Asian Pac J Cancer Prev 21(11):3251-3258. doi: 10.31557/APJCP.2020.21.11.3251, 2020. (PMID: 33247682)
  15. Qureshi MA, Khan S, Sharafat S, Quraishy MS. Common Cancers in Karachi, Pakistan: 2010-2019 Cancer Data from the Dow Cancer Registry. Pak J Med Sci 36(7):1572-1578. doi: 10.12669/pjms.36.7.3056, 2020. (PMID: 33235577)
  16. Zohaib A, Zhang J, Saqib M, Athar MA, Hussain MH, Chen J, Sial AU, Tayyab MH, Batool M, Khan S, Luo Y, Waruhiu C, Taj Z, Hayder Z, Ahmed R, Siddique AB, Yang X, Qureshi MA, Ujjan IU, Lail A, Khan I; Sajjad-Ur-Rahman; Zhang T, Deng F, Shi Z, Shen S. Serologic Evidence of Severe Fever with Thrombocytopenia Syndrome Virus and Related Viruses in Pakistan. Emerg Infect Dis 26(7):1513-1516. doi: 10.3201/eid2607.190611, 2020. (PMID: 32568060)
  17. Shabbir A, Qureshi MA, Akram S, Mirza T. Spectrum of Preneoplastic and Neoplastic lesions of intestine in a Tertiary Care Hospital of Karachi, Pakistan. Pak J Med Sci 36(2):75-79. doi: 10.12669/pjms.36.2.687, 2020. (PMID: 32063935)
  18. Ashfaq-Khan M, Aslam M, Qureshi MA, Senkowski MS, Yen-Weng S, Strand S, Kim YO, Pickert G, Schattenberg JM, Schuppan D. Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease. Sci Rep 9(1):17463. doi: 10.1038/s41598-019-53323-x, 2019. (PMID: 31767938)
  19. Shabbir A, Qureshi MA, Khalid AB, Mirza T, Shaikh A, Hasan SM. Gastric adenocarcinoma expressing human epidermal growth factor receptor in South Asian population. Saudi J Gastroenterol. 24(5):289-293. doi: 10.4103/sjg.SJG_23_18, 2018. (PMID: 29806596)
  20. Khan S, Zahid M, Qureshi MA, Mughal MN, Ujjan ID. HIV-1 genetic diversity, geographical linkages and antiretroviral drug resistance among individuals from Pakistan. Arch Virol 163(1):33-40. doi: 10.1007/s00705-017-3564-1, 2018. (PMID: 28942522)
  21. Gao X, Lampraki EM, Al-Khalidi S, Qureshi MA, Desai R, Wilson JB. N-acetylcysteine (NAC) ameliorates Epstein-Barr virus latent membrane protein 1 induced chronic inflammation. PLoS One. 2017 Dec 11;12(12):e0189167. doi: 10.1371/journal.pone.0189167, 2017. (PMID: 29228057)
  22. Sikandar B, Qureshi MA, Naseem S, Khan S, Mirza T. Increased Tumour Infiltration of CD4+ and CD8+ T-Lymphocytes in Patients with Triple Negative Breast Cancer Suggests Susceptibility to Immune Therapy. Asian Pac J Cancer Prev 18(7):1827-1832. doi: 10.22034/APJCP.2017.18.7.1827, 2017. (PMID: 28749113)
  23. Shabbir A, Qureshi MA, Mirza T, Khalid AB. Human epidermal growth factor (Her-2) in gastric and colorectal adenocarcinoma. J Pak Med Assoc 67(7):1085-1090. PMID: 28770892, 2017.
    24. (PMID: 28770892)
  24. Qureshi MA, Kim YO, Schuppan D. Hepatocellular carcinoma in nonalcoholic fatty liver disease: A link between oxidative stress and T-cell suppression. Hepatology 64(5):1794-1797. doi: 10.1002/hep.28815, 2016. (PMID: 27629157)
  25. Qureshi MA, Mirza T, Khan S, Sikandar B, Zahid M, Aftab M, Mohsin S, Sharafat S, Avesi L, Hassan S. Cancer patterns in Karachi (all districts), Pakistan: First results (2010-2015) from a Pathology based cancer registry of the largest government-run diagnostic and reference center of Karachi. Cancer Epidemiol 44:114-122. doi: 10.1016/j.canep.2016.08.011, 2016. (PMID: 27566468)
  26. Shabbir A, Mirza T, Khalid AB, Qureshi MA, Asim SA. Frequency of Her2/neu expression in colorectal adenocarcinoma: a study from developing South Asian Country. BMC Cancer 16(1):855. doi: 10.1186/s12885-016-2912-y, 2016. (PMID: 27821098)
  27. Qureshi MA, Khan S, Ujjan ID, Iqbal A, Khan R, Khan BA. Quantitative Analyses of Esophageal Cancer Research in Pakistan. Asian Pac J Cancer Prev 17(7):3117-22, 2016. (PMID: 27509939)
  28. Qureshi MA, Khan S, Zahid M, Ali Z. HIV/AIDS registration in Pakistan. Lancet Infect Dis 15(6):635-6. doi: 10.1016/S1473-3099(15)00024-9, 2015. (PMID: 26008838)
  29. Sikandar B, Qureshi MA, Mirza T, Khan S, Avesi L. Differential immune cell densities in ductal carcinoma In-Situ and invasive breast cancer: Possible role of leukocytes in early stages of carcinogenesis. Pak J Med Sci 31(2):274-9. doi: 10.12669/pjms.312.6481, 2015. (PMID: 26101474)
  30. Qureshi MA, Mirza T, Khan S, Sikandar B. Cancer registration in Pakistan: a dilemma that needs to be resolved. Int J Cancer 136(6):E773. doi: 10.1002/ijc.29253, 2015. (PMID: 25283161)
  31. Ujjan ID, Akhund AA, Saboor M, Qureshi MA, Khan S. Cytogenetic and Molecular Analyses of Philadelphia Chromosome Variants in CML (chronic myeloid leukemia) Patients from Sindh using Karyotyping and RT-PCR. Pak J Med Sci 31(4):936-40. doi: 10.12669/pjms.314.7261, 2015.
    32. (PMID: 26430433)
  32. Mushtaq A, Khatoon S, Qureshi MA. Use of Corticosteroids in the management of Idiopathic Pulmonary Haemosiderosis: Do we have enough evidence. Pak J Med Sci 31(2):487-9. doi: 10.12669/pjms.312.7135, 2015. (PMID: 26101518)
  33. Qureshi MA, Qureshi MS, Khanani MR. Health and research in Pakistan. Lancet 382(9900):1245. doi: 10.1016/S0140-6736(13)62091-7, 2013. (PMID: 24120198)
  34. Mushtaq A, Abid M, Qureshi MA. Is prophylactic antibiotic treatment justified in neonates? J Pak Med Assoc 62(8):856-7, 2012. (PMID: 23862269)
  35. Hannigan A, Qureshi AM, Nixon C, Tsimbouri PM, Jones S, Philbey AW, Wilson JB. Lymphocyte deficiency limits Epstein-Barr virus latent membrane protein 1 induced chronic inflammation and carcinogenic pathology in vivo. Mol Cancer 10(1):11. doi: 10.1186/1476-4598-10-11, 2011.
    36. (PMID: 21291541)
  36. Qureshi AM, Hannigan A, Campbell D, Nixon C, Wilson JB. Chitinase-like proteins are autoantigens in a model of inflammation-promoted incipient neoplasia. Genes Cancer 2(1):74-87. doi: 10.1177/1947601911402681, 2011. (PMID: 21779482)
⦁ Previous/Current Research Funding (Including VCSFI funding)